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Erectile dysfunction as a predictor of early stage of coronary artery disease
Babak Baharvand Ahmadi1, Mehrdad Namdari1, Hirbod Mobarakeh2
1Department of Cardiology, Lorestan University of Medical Sciences, Lorestan, Iran.
Insights
Erectile dysfunction (ED) is more prevalent in patients with coronary artery disease (CAD). ED severity correlates with the number of diseased coronary vessels, suggesting ED may indicate atherosclerosis risk.
Area of Science:
- Cardiology
- Urology
- Vascular Health
Background:
- Early diagnosis of coronary artery disease (CAD) is crucial for reducing mortality.
- Investigating the link between erectile dysfunction (ED) and CAD is important for risk assessment.
Purpose of the Study:
- To explore the association between erectile dysfunction (ED) and coronary artery disease (CAD).
Main Methods:
- 200 patients were categorized into four groups based on coronary angiography: one-vessel disease (n=59), two-vessel disease (n=40), three-vessel disease (n=50), and controls (n=51).
- The International Index of Erectile Function (IIEF) was used to assess sexual function and ED over the past six months.
Main Results:
- The prevalence of ED was significantly higher in CAD patients (75.16%) compared to controls (60.8%; p=0.041).
- A significant direct correlation was found between the number of involved coronary vessels and ED severity (r=0.183; p=0.010).
- ED prevalence increased with age in CAD patients.
Conclusions:
- ED severity is associated with the extent of coronary artery disease, as indicated by angiography.
- Erectile dysfunction may serve as a potential early marker for atherosclerosis and the development of CAD.
Background:
Diagnosis of coronary artery disease (CAD) in early stages is vital in decreasing mortality by reducing the risk factors. The aim of this study was to investigate the association between erectile dysfunction (ED) and CAD.
Methods:
A total of 200 patients were divided into four groups according to their angiography results: Group 1 (G1, n = 59): patients with one-vessel disease (1-VD); Group 2 (G2, n = 40): patients with two-vessel disease (2-VD); Group 3 (G3, n = 50): patients with three-vessel disease (3-VD); and controls (C, n = 51) without any coronary disease. The International Index of Erectile Function (IIEF) was completed for all the patients to assess their sexual function and ED in the last 6 months.
Results:
Mean age of the participants was 57.69 ± 12.466 years. The prevalence of ED in the CAD patients was significantly higher than that of the controls (75.16% vs. 60.8%; p value = 0.041). There was a significant direct correlation between the number of involved vessels in the CAD patients and ED severity (r: 0.183; p value = 0.010), and the ED rate increased with age.
Conclusion:
In conclusion, ED severity correlated with the number of involved vessels documented by coronary angiography. Consequently, ED may be considered a possible marker for the development of atherosclerosis and CAD.
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