Related Experiment Video
Updated: Apr 15, 2026

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Distraction magnitude and frequency affects the outcome in juvenile idiopathic patients with growth rods: finite
Aakash Agarwal1, Amanda Zakeri1, Anand K Agarwal1
1Engineering Center for Orthopaedic Research Excellence (ECORE), Department of Bioengineering and Orthopaedics surgery, Colleges of Engineering and Medicine, University of Toledo, 5051 Nitschke Hall MS 303, 2801 W. Bancroft St., Toledo, OH 43606, USA.
Background Context:
Growth rods are used to limit the progression of scoliosis without restraining the opportunity for the spine to grow. However, major complications like rod breakage, screw loosening, and altered sagittal contour have been encountered.
Objective:
To analyse the effect of the magnitude of distraction forces on the T1-S1 growth, maximum von Mises stresses on the rods, sagittal contours, and load at the pedicle screw-bone interface and quantify the maximum stresses on the rod for a period of 24 months using different frequencies of distraction in a representative scoliotic spine model.
Study Design:
A representative finite element model of a juvenile scoliotic spine was used to study the effect of magnitude and frequency of distraction on growth rods.
Methods:
A representative scoliotic model was developed and instrumented using proximal foundation, distal foundation, and rods. Part 1: simulation steps comprised 6 months of growth under various distraction forces to analyze effects of distraction force on the biomechanics of the spine and instrument. Part 2: simulation steps comprised 24 months of growth under various intervals of distraction to analyze effects of distraction interval on the propensity of rod fracture.
Results:
Part 1: an optimal distraction force exists for which the growth is sustained with minimum stress on the rod, lower loads at screw-bone interface, and unaltered sagittal contours. Part 2: the stresses on the rods were highest for 12-month distraction (2 distractions in 2 years) and lowest for 2-month distraction (12 distractions in 2 years).
Conclusions:
The data and trend suggest that as the distraction forces vary so do the effects on spinal growth. The results of this study also signify the importance of shorter distraction period in reducing the stresses on the rods.
Related Concept Videos
Normal Strain under Axial Loading
Temperature Dependent Deformation
Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity
Deformation of Member under Multiple Loadings
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
Bending of Curved Members - Strain Analysis
The important part of bending analysis for such a member...

