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Updated: Apr 15, 2026

A Rhodopsin Transport Assay by High-Content Imaging Analysis
Published on: January 16, 2019
Rhodopsin on tracks: new ways to go in signaling
1Laboratory of Biomolecular Research, Paul Scherrer Institute, 5232 Villigen, Switzerland; Department of Biology, ETH Zurich, Wolfgang-Pauli-Str. 27, 8093 Zürich, Switzerland.
Abstract:
In this issue of Structure, Gunkel et al. describe cryoelectron tomography analysis of the nano-organization of the G protein-coupled receptor (GPCR) rhodopsin in the rod photoreceptor disk membranes in a near-native environment. Their data strongly suggest that rhodopsin is organized in the native rod disk as dimers arranged in parallel tracks aligned to the incisure.
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