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[Comparative study of clinical features between unilateral and bilateral orbital IgG4-related disease]
I Coloma-González1, A Ceriotto1, J Flores-Preciado1
1Servicio de Órbita, Párpados y Vía Lagrimal, Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera IAP, México D.F. México.
Objective:
Descriptive and comparative study of patients with orbital IgG4-related disease.
Material And Methods:
A review and analysis of the cases diagnosed with inflammatory orbital lesion related to IgG4 by the Ophthalmic Pathology Service in the Dr. Luis Sánchez Bulnes Hospital.
Results:
A total of 9 cases were found, in which 66% were women, and with a mean age of 48 years and time to diagnosis of 2 years. Unilateral involvement was observed in 56% of cases. All the females experienced pain, and there was an optimal response to corticosteroid treatment in 100% of patients who required medical treatment (one case showed spontaneous resolution). In bilateral cases (44%), only 25% were female, and none had pain as a presenting symptom. Furthermore, 25% of these patients required a combination with immunosuppressants to control inflammation.
Conclusions:
Clinical presentation of patients with unilateral orbital IgG4-related disease differs from those with bilateral involvement.
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