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Updated: Jul 5, 2026

Visualization of UV-induced Replication Intermediates in E. coli using Two-dimensional Agarose-gel Analysis
Published on: December 21, 2010
[On the possibility of analysis of biopolymer fragments by tunneling microscopy]
Abstract:
An image of fragmented sequence of biopolymer molecules by example of bacterial DNA in vivo (in atmosphere air) was received by scanning tunneling microscopy. An air adsorbate (mainly water vapors) that covers the molecule's surface gives rise to local tunnel conductivity and by virtue of adsorption selectivity indirectly reflects local conductance of fragments that consist of different rows of various atoms, supporting their tunnel conductivity. Having processed experimental data fragment images are obtained with scaled-up topography characteristics for their further identification.

