Related Experiment Video
Updated: Apr 15, 2026

Enhanced Genetic Analysis of Single Human Bioparticles Recovered by Simplified Micromanipulation from Forensic ‘Touch DNA’ Evidence
Published on: March 9, 2015
Automated DNA profile analysis
1Forensic Pathology Unit, University of Leicester, Robert Kilpatrick Building Leicester Royal Infirmary, LE2 7LX, Leicester, United Kingdom, eamg1@le.ac.uk.
Abstract:
DNA profile analysis is not a simple process. Stringent demands are placed on the accuracy and consistency of forensic evidence so that complex, robust, and reproducible guidelines are necessary to assist the analyst and ensure mistakes are eliminated before a final profile is reported. The guidelines used for forensic DNA profile interpretation are formulated by investigation and statistical evaluation of all aspects of the analytical procedure. All the resulting rules, formulas, and thresholds are perfectly suited to programming of "expert systems"-software programs that imitate the human expert in decision-based processes to formulate a conclusion. Expert systems in forensic DNA analysis will contribute greatly to this field by increasing analytical throughput. The net result of this will be an increase in the human resources available for the research and development of improved methodologies, to ensure that forensic DNA profiling continues to advance at its current impressive rate.
Related Concept Videos
DNA Microarrays
Automated Microbial Diagnostics
Sanger Sequencing
DNA Isolation

