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Related Concept Videos

Cancer02:18

Cancer

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Cancer Prevention02:59

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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What is Cancer?02:12

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Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
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Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
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Breast Cancer Version 2.2015.

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    This summary is machine-generated.

    This NCCN Guidelines update focuses on breast cancer treatment for women. It details recommendations for managing locoregional breast cancer, including surgery and radiation therapy for early stages.

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    Area of Science:

    • Oncology
    • Medical Guidelines

    Background:

    • Breast cancer is a leading cause of cancer death in US women.
    • Comprehensive management involves local and systemic therapies.
    • NCCN Guidelines provide evidence-based recommendations for cancer care.

    Purpose of the Study:

    • To present updated recommendations for the locoregional management of breast cancer.
    • To focus on clinical stages I, II, and IIIA (T3N1M0) tumors.
    • To guide clinicians in treating early-stage breast cancer.

    Main Methods:

    • Review of current evidence and clinical practice.
    • Development of consensus-based recommendations.
    • Adherence to National Comprehensive Cancer Network (NCCN) protocols.

    Main Results:

    • Specific recommendations for surgery and radiation therapy for locoregional breast cancer.
    • Guidance on treatment selection based on tumor stage and characteristics.
    • Integration of systemic therapy considerations for locoregional disease management.

    Conclusions:

    • Optimal locoregional management is crucial for early-stage breast cancer outcomes.
    • Adherence to NCCN Guidelines ensures standardized, high-quality care.
    • Continued updates reflect advancements in breast cancer treatment.