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Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
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Olfactory dysfunction in Iranian diabetic patients.

Jalal Mehdizadeh Seraj1, Siamak Mehdizadeh Seraj2, Hamidreza Zakeri3

  • 1Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran. mehdizaj@yahoo.com.

Acta Medica Iranica
|April 15, 2015
PubMed
Summary
This summary is machine-generated.

Diabetic patients often experience olfactory dysfunction, impacting quality of life. This study found 60% of diabetics had impaired smell, but it wasn't linked to diabetes complications.

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Area of Science:

  • Endocrinology
  • Neurology
  • Ophthalmology

Background:

  • Diabetes mellitus is associated with various complications.
  • Olfactory dysfunction is a recognized but often overlooked complication of diabetes.
  • The impact of olfactory dysfunction on diabetic patients' quality of life is significant.

Purpose of the Study:

  • To determine the prevalence and severity of olfactory dysfunction in diabetic patients.
  • To investigate the association between olfactory dysfunction and microangiopathic complications (neuropathy, nephropathy, retinopathy) in diabetes.
  • To exclude confounding factors in the assessment of olfactory dysfunction.

Main Methods:

  • A case-control study involving 60 subjects (30 diabetic patients, 30 controls).
  • Olfactory threshold was assessed using the absorbent perfumer's paper strips method.
  • Confounding factors were carefully excluded to ensure reliable results.

Main Results:

  • A significant prevalence of olfactory dysfunction was observed in 60% of diabetic patients.
  • A statistically significant difference (P<0.01) in olfactory threshold was found between diabetic and control groups.
  • No significant associations were identified between olfactory dysfunction and age, sex, diabetes duration, or microangiopathic complications.

Conclusions:

  • Olfactory dysfunction is a common complication in diabetic patients.
  • The study highlights a significant impairment in smell among diabetics compared to controls.
  • Olfactory dysfunction in diabetes appears independent of common microangiopathic complications and demographic factors.