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Updated: Apr 15, 2026

Aptamer-Based Target Detection Facilitated by a 3-Stage G-Quadruplex Isothermal Exponential Amplification Reaction
Published on: October 6, 2022
Turn-on and label-free fluorescence detection of lead ions based on target-induced G-quadruplex formation
Lijun Xu1, Xiaoqiang Shen, Shanni Hong
1Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Collaborative Innovation Center of Suzhou Nano Science and Technology, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, P. R. China. rjpei2011@sinano.ac.cn.
Abstract:
Using a guanine-rich sequence (AGRO100) and N-methyl mesoporphyrin IX (NMM), a turn-on and label-free fluorescent Pb(2+) sensor with high sensitivity and low background fluorescence was presented as a representative of five turn-on sensing systems.
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