Related Experiment Video
Updated: Apr 14, 2026

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
Published on: February 6, 2015
Reviewing cancer care team effectiveness
Stephen H Taplin1, Sallie Weaver2, Eduardo Salas2
1National Cancer Institute, Bethesda; Johns Hopkins University School of Medicine, Armstrong Institute for Patient Safety and Quality, Baltimore; Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD; University of Central Florida, Orlando, FL; American Society of Clinical Oncology, Alexandria, VA; and Scripps Clinic, La Jolla, Ca taplins@mail.nih.gov.
Multidisciplinary care teams (MDTs) show promise in improving cancer screening and treatment planning. However, their impact on patient survival and care costs requires further investigation.
Area of Science:
- Oncology
- Healthcare Management
- Team-Based Care
Background:
- Cancer management is complex, involving diverse specialists and varying patient needs.
- Team-based approaches are effective in other fields but under-evaluated in oncology.
- Optimizing cancer care delivery requires understanding team effectiveness.
Purpose of the Study:
- To systematically review the effectiveness of multidisciplinary care teams (MDTs) in oncology.
- To identify patient-level metrics associated with MDT interventions in cancer care.
- To evaluate the impact of MDTs on screening, treatment, palliative, and end-of-life care.
Main Methods:
- Systematic literature review of studies published between 2009 and 2014.
- Included studies focused on teams with clear membership and patient-level cancer care metrics.
- Evaluated 16 studies covering screening, diagnosis, treatment, palliative, and end-of-life care.
Main Results:
- MDTs improved cancer screening rates and reduced follow-up times.
- MDT case discussions enhanced therapy planning, preoperative assessment, and medication adherence.
- No convincing evidence was found for MDTs impacting patient survival or care costs.
Conclusions:
- Further research is needed on the association between MDT processes, structures, and outcomes.
- Investigate the impact of MDTs on the efficiency of cancer care delivery.
- Explore the relationship between MDTs and patient mortality in oncology.
Related Concept Videos
Cancer Survival Analysis
Interdisciplinary Care: The Health Care Team-I
Physicians
The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution...
Interdisciplinary Care: The Health Care Team-II
Physical Therapist
A physical therapist (PT) aims to restore function or prevent additional impairment in a patient following an injury or disease. Massage, heat, cold, water, sonar waves, exercises, and electrical stimulation are some treatments used by PTs to treat...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies
Patient-centered Care