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Updated: Apr 14, 2026

A Multimodal Wide-Field Fourier-Transform Raman Microscope
Published on: December 30, 2025
Raman Imaging from Microscopy to Nanoscopy, and to Macroscopy.
Xiaoshan Zheng1, Cheng Zong1, Mengxi Xu1
1State Key Laboratory of Physical Chemistry of Solid Surfaces, The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China.
Raman spectroscopy offers unique fingerprint identification for multiplex analysis. Recent advances in Raman microscopy enhance its capabilities for diverse sample imaging, with a focus on future technical and application developments.
Area of Science:
- Analytical Chemistry
- Spectroscopy
- Materials Science
Background:
- Raman spectroscopy provides intrinsic molecular fingerprint information.
- Its narrow bandwidth and low background make it suitable for multiplex analysis.
- Raman microscopy is increasingly vital for imaging diverse samples.
Purpose of the Study:
- To critically review recent advances in Raman imaging techniques.
- To discuss the advantages and limitations of current Raman imaging methods.
- To highlight future directions in Raman imaging technology and applications.
Main Methods:
- Review of recent scientific literature on Raman imaging.
- Critical analysis of established and emerging Raman microscopy techniques.
- Discussion of technical challenges and application potentials.
Main Results:
- Identification of key recent advancements in Raman imaging.
- Evaluation of the strengths and weaknesses of current Raman microscopy approaches.
- Outline of promising future developments in the field.
Conclusions:
- Raman microscopy is a powerful imaging technique with broad applicability.
- Ongoing technical innovations are expanding its capabilities.
- Future research should focus on both technical refinement and novel applications.
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