Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Local Anesthetics: Clinical Application as Epidural Anesthesia

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

Local Anesthetics: Clinical Application as Spinal Anesthesia

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...

Randomized Experiments

Randomized Experiments

The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Infrared thermographic assessment of cutaneous temperature changes during labour epidural analgesia initiation: an observational pilot study.

International journal of obstetric anesthesia·2025

Same author

Development of a Novel Non-invasive Metabolomics Assay to Predict Implantation Potential of Human Embryos.

Reproductive sciences (Thousand Oaks, Calif.)·2024

Same author

A comparative assessment of Patient Safety Culture in a tertiary maternity hospital.

Irish medical journal·2024

Same author

Use of the Obstetric Quality-of-Recovery score (ObsQoR-11) to measure the impact of an enhanced recovery programme for elective caesarean section.

International journal of obstetric anesthesia·2023

Same author

Management of an Unstable Preterm COVID-19 Pregnant Woman with Emergency Caesarean Delivery.

Irish medical journal·2023

Same author

Hereditary haemorrhagic telangiectasia and neuraxial anaesthesia in pregnancy: when should magnetic resonance imaging be performed?

Anaesthesia reports·2023

Search research articles

Related Experiment Video

Updated: Apr 14, 2026

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy

Published on: January 31, 2025

A randomised controlled trial using the Epidrum for labour epidurals.

M Deighan, D O Briain, H Shakeban

Irish Medical Journal

|April 17, 2015

Summary

The Epidrum device did not improve epidural analgesia success rates or reduce complications in laboring patients. This study found no significant benefits of using the Epidrum compared to standard techniques for epidural placement.

More Related Videos

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

Related Experiment Videos

Last Updated: Apr 14, 2026

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy

Author Spotlight: Enhancing Success of Ultrasound-Guided Neuraxial Anesthesia in Cases with Difficult Anatomy

Published on: January 31, 2025

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP

Published on: January 27, 2010

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

Area of Science:

Obstetrics and Gynecology
Anesthesiology
Medical Devices

Background:

Epidural analgesia is a common method for pain relief during labor.
Improving the success rate and reducing complications of epidural placement is crucial for patient care.

Purpose of the Study:

To evaluate if the Epidrum device enhances epidural analgesia success rates.
To determine if Epidrum use reduces morbidity associated with epidural placement.

Main Methods:

A randomized controlled trial involving 300 parturients requesting epidural analgesia.
150 subjects received epidurals using the Epidrum, while 150 used the standard technique.
Data collected included demographics, operator experience, number of attempts, and complication rates.

Main Results:

The Epidrum group showed a higher failure rate (6%) compared to the control group (0%, P = 0.003).
Accidental dural puncture occurred in 2.66% of the Epidrum group versus 0% in the control group (P = 0.060).
No significant difference was observed in catheter re-siting rates between the groups.

Conclusions:

The study findings do not support the use of the Epidrum for improving epidural placement success.
The Epidrum did not demonstrate a reduction in morbidity compared to standard epidural techniques.