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Updated: Apr 14, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Primary squamous cell carcinoma of bladder exstrophy in an adult
Suresh Bhat1, Manjunatha Sathyanarayanaprasad1, Fredrick Paul1
1Department of Urology, Government Medical College, Kottayam, Kerala, India.
Abstract:
Exstrophy of the urinary bladder is a rare congential anomaly. The most common malignancy is an adenocarcinoma in these patients. Squamous cell carcinoma (SCC) occurring in these patients is uncommon and usually has a bad prognosis. The management of these patients is challenging and may require extensive reconstructive procedures. We report a case of SCC in a corrected bladder exstrophy patient who presented with an ulcerated mass in the lower abdomen extending to the base of the penis. Six months after extensive radical ablative surgery with reconstruction of the abdominal wall, the patient remained free of recurrence.
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