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Related Concept Videos

Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

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Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
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Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
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Related Experiment Video

Updated: Apr 14, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
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[Evaluation of left ventricular function by systolic time intervals].

Ikram Kammoun, Lilia Zakhama, Houcem Boussaidi

    La Tunisie Medicale
    |April 17, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Systolic time intervals (STI) offer a simpler method for assessing left ventricular systolic function. A pre-ejectional time to ejection time (PET/ET) ratio of 0.33 can help diagnose reduced ejection fraction.

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    Area of Science:

    • Cardiology
    • Echocardiography
    • Physiology

    Background:

    • Left ventricular systolic function is typically assessed using ejection fraction (EF).
    • Advanced echocardiography techniques like 3D echo and speckle tracking require high technical skill and good image quality.
    • Systolic time intervals (STI), including pre-ejectional time (PET) and ejection time (ET), are proposed for evaluating myocardial performance, especially in heart failure.

    Purpose of the Study:

    • To establish the correlation between left ventricular ejection fraction (LVEF) and STI.
    • To determine a cut-off value for the PET/ET ratio to diagnose LVEF below 35%.

    Main Methods:

    • 109 patients underwent STI and LVEF measurements using the Simpson biplane method.
    • Patients were in sinus rhythm with heart rate < 100 bpm.
    • Exclusion criteria included atrial fibrillation, pacemakers, and prosthetic valves.

    Main Results:

    • STI measurements demonstrated 100% feasibility.
    • A significant negative correlation was found between PET and LVEF (r=-0.49, p<0.0001).
    • The PET/ET ratio showed a significant negative correlation with LVEF (r=-0.63, p<0.0001).
    • Receiver operating curve analysis identified a PET/ET ratio cut-off of 0.33 for diagnosing LVEF < 35%, with 85% sensitivity and 78% specificity.

    Conclusions:

    • STI are easily obtainable and valuable when echocardiographic windows are poor.
    • STI serve as a practical alternative for assessing systolic left ventricular function.
    • STI can effectively detect alterations in LVEF.