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Levels of evidence: a comparison between top medical journals and general pediatric journals
Dustin A Jacobson1, Kunal Bhanot2, Blake Yarascavitch3
1Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada. jacobson.dustin@gmail.com.
Insights
Pediatric clinical literature in high-impact journals offers higher levels of evidence (LOE) and better-quality randomized control trials. Focusing on these resources can improve clinical decision-making.
Area of Science:
- Medical Research
- Clinical Evidence
- Pediatric Literature
Background:
- Clinicians require high levels of evidence (LOE) due to the vast amount of published research.
- Assessing LOE in pediatric literature is crucial for effective clinical practice.
Purpose of the Study:
- To determine the level of evidence (LOE) in pediatric literature.
- To compare LOE between general pediatric journals and high-impact clinical journals.
Main Methods:
- Reviewed pediatric articles from April 2011 to March 2012 in high-impact clinical journals (HICJ) and general pediatric journals (GPJ).
- Evaluated articles for LOE, subspecialty, author count, and study centers.
- Assessed eligible Level I randomized control trials using Consolidated Standards of Reporting Trials (CONSORT) guidelines.
Main Results:
- 804 of 6511 articles met inclusion criteria (68 in HICJ, 736 in GPJ).
- Pediatric articles in The Lancet showed significantly higher LOE than GPJ (p < 0.05).
- HICJ demonstrated significantly higher average CONSORT scores than GPJ (15.2 vs. 13.6, p < 0.001).
Conclusions:
- High-impact clinical journals (HICJ) provide the highest LOE and quality for pediatric randomized control trials.
- Pediatric studies in HICJ represent a small fraction of published data.
- Adhering to CONSORT criteria and promoting high LOE studies can enhance clinical impact.
Background:
Given the large number of publications in all fields of practice, it is essential that clinicians focus on the resources that provide the highest level of evidence (LOE). We sought to determine the LOE that exists in the field of pediatrics, present in the general pediatric as well as high impact clinical literature.
Methods:
Clinical pediatric literature, published between April 2011 and March 2012 inclusive in high-impact clinical journals (HICJ) (New England Journal of Medicine, Journal of the American Medical Association, & The Lancet) and the highest-impact general pediatric journals (GPJ) (Pediatrics, Journal of Pediatrics, & Archives of Pediatrics & Adolescent Medicine), was assessed. In addition to the LOE, articles were evaluated on criteria including subspecialty within pediatrics, number of authors, number of centers, and other parameters. Eligible level I randomized control trials were appraised using the Consolidated Standards of Reporting Trials (CONSORT) guidelines.
Results:
Of 6511 articles screened, 804 met inclusion criteria (68 in HICJ and 736 in GPJ). On average, LOE in pediatrics-focused articles within The Lancet were significantly higher than all GPJ (p < 0.05). Average CONSORT scores were significantly higher in HICJ vs. GPJ (15.2 vs. 13.6, respectively, p < 0.001).
Conclusions:
LOE and quality of randomized control trials within the pediatric field is highest within HICJ, however, only represent a small proportion of data published. Following CONSORT criteria, and promoting studies of high LOE may allow authors and readers to turn to journals and articles of greater clinical impact.
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