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SNPchiMp v.3: integrating and standardizing single nucleotide polymorphism data for livestock species
Ezequiel L Nicolazzi1, Andrea Caprera2, Nelson Nazzicari3
1Bioinformatics and Biostatistical Genomics group, Fondazione Parco Tecnologico Padano, Via Einstein, Loc. Cascina Codazza, 26900, Lodi, Italy. ezequiel.nicolazzi@tecnoparco.org.
SNPchiMp v.3 standardizes and integrates single nucleotide polymorphism (SNP) array data for six major livestock species. This accessible web tool aids genetic improvement and research by linking diverse array information with public databases.
Area of Science:
- Livestock genomics
- Bioinformatics
- Animal breeding
Background:
- Genomic information is crucial for livestock genetic improvement and association studies.
- Numerous single nucleotide polymorphism (SNP) arrays exist for livestock, varying in content and density.
- Lack of standardization and integration for array-specific and species-specific SNP data hinders usability.
Purpose of the Study:
- To present SNPchiMp v.3, a solution for standardizing and integrating SNP array data.
- To address the challenges of diverse SNP array content and species-specific information.
- To provide a user-friendly platform for livestock genomic data management.
Main Methods:
- Collected original data from SNP array producers and genome consortia.
- Stored data in a MySQL database.
- Developed an open-access web tool linking the database to public resources.
Main Results:
- SNPchiMp v.3 provides standardized and integrated genomic data for cattle, pigs, horses, sheep, goats, and chickens.
- The platform ensures fast retrieval of within/across SNP array data.
- SNPchiMp v.3 enables user-friendly annotation of SNP array data.
Conclusions:
- SNPchiMp v.3 facilitates easy integration and standardization of livestock genomic data for research and industry.
- Users can seamlessly link array producer information with public database data.
- The tool is recognized as an Ensembl E!mpowered tool, highlighting its value and integration with public resources.
Related Concept Videos
Single Nucleotide Polymorphisms-SNPs
Comparing Copy Number Variations and SNPs
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...

