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A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
Published on: August 28, 2014
The evolving paradigm of revascularization for wound healing: which intervention for which wound?
1University of Pennsylvania School of Medicine, Philadelphia, Pa;
Abstract:
Chronic limb ischemia (CLI) presents a therapeutic challenge. A collaborative multidisciplinary model utilizes the collective skills of the vascular surgeon, podiatrist, and plastic surgeon to achieve optimal outcomes. As treatment paradigms continue to evolve toward minimally invasive approaches, a thoughtful comparison of the available options is essential for wound care specialists. Minimally invasive, catheter-based options offer less morbidity with reduced patency compared to traditional, open bypass. Individualized selection of the most appropriate revascularization option should be made after careful consideration of the wound severity, anatomic location of occlusive disease and patient comorbidities.
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