[The use of naniprus (sodium nitroprusside) in therapy-resistant arterial hypertension]

Naniprus (sodium nitroprusside) was shown to be clinically effective in the treatment of arterial hypertension and to have a favourable effect on the central and peripheral hemodynamics (a decrease of the total peripheral vascular resistance, of the energy consumption by the myocardium, an increase of the stroke volume, stroke index, and cardiac output). It is concluded that naniprus can be used for arterial pressure correction in the treatment-resistant patterns of hypertension, especially in combination with beta-blockers preventing the "after-action effect" (ejection at the moment of catecholamine infusion discontinuance).