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Updated: Apr 14, 2026

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants
Published on: December 14, 2014
Less sickness with more motion and/or mental distraction.
1TNO Perceptual and Cognitive Systems, P.O. Box 23, 3769 ZG Soesterberg, Netherlands Research Institute MOVE, Faculty of Human Movement Sciences, VU University, Amsterdam, Netherlands. Tel.: +31 888 66 59 25;
Motion sickness can be reduced by adding vibration and mental distraction. These methods significantly decrease discomfort and improve performance, offering alternatives to medication.
Area of Science:
- Vestibular science
- Human factors engineering
- Neuroscience
Background:
- Motion sickness negatively impacts passenger comfort and crew performance.
- Current countermeasures, primarily medication, often cause undesirable side effects.
Purpose of the Study:
- To investigate the efficacy of adding inherent non-sickening vibration and mental distraction in reducing motion sickness.
- To quantify the combined and individual effects of these interventions.
Main Methods:
- Eighteen blindfolded subjects underwent off-vertical axis rotation (OVAR) with a vibrating headrest.
- Interventions (vibration, mental distraction task) were tested individually and in combination.
- Subjective sickness ratings and objective task performance were used to quantify effects.
Main Results:
- Head vibration reduced sickness by 25%, mental distraction by 19%, and their combination by 39%.
- Task performance was inversely correlated with sickness levels.
- Sixteen subjects completed the study under comparable conditions.
Conclusions:
- Low-frequency motion sickness can be effectively mitigated by high-frequency vibration and mental distraction.
- Vibration's effect may be explained by the central nervous system's internal model for motion control optimization.
- These non-pharmacological methods offer promising alternatives for managing motion sickness.
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