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Anaplastic lymphoma kinase-positive large B-cell lymphoma: a potential diagnostic pitfall
Hong Yu, Junxing Huang, Juanjuan Sun
1Department of Pathology, Cancer Hospital of Fudan University, Shanghai 200032, China.
Abstract:
Anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK + LBCL) is a rare variant of LBCL with an abnormal immunophenotype, which is easily misdiagnosed as carcinoma or plasma cell neoplasm. Here, we present two cases of ALK + LBCL in the lymph node; describe their clinical, pathological, and immunophenotype features; and compare them with those of the reported cases.
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