Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

751
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
751
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

926
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
926
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

2.3K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
2.3K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

1.5K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.5K
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

1.6K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Letter to the Editor: Single-cell and multi-omics integrative modeling identifies mitochondrial gene HSPE1 as a therapeutic target in osteosarcoma.

Journal of translational medicine·2026
Same author

Emerging quantum critical phase in a cluster spin-glass.

National science review·2026
Same author

Skin-mimetic bilayer hydrogel normalizes diabetic wound healing by orchestrating inflammatory cell dynamics: An early intervention strategy.

Bioactive materials·2026
Same author

Synergistic 3D-bioprinted scaffold with multi-level adaptability for vascularized bone regeneration via osteogenesis-angiogenesis coupling.

Materials today. Bio·2026
Same author

Fourier ptychographic coherence scanning interferometry for 3D morphology of high aspect ratio and composite micro-trenches.

Light, science & applications·2026
Same author

Association between dietary index for gut microbiota and hypertension: a cross-sectional NHANES-based study.

Journal of hypertension·2025

Related Experiment Video

Updated: Apr 14, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
08:10

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Published on: April 9, 2012

82.3K

USA's expanded overseas tuberculosis screening program: a retrospective study in China.

Shaojun Liang1, Jianming Zhang2, Longfei Hu3

  • 1Guangdong International Travel Healthcare Center, 5/F, Eastern Tower, Poly Building, 59 Huali Road, Zhujiang New City, Guangzhou, Guangdong, 510600, PR China. samzjxc@163.com.

BMC Public Health
|April 18, 2015
PubMed
Summary

The 2009 Tuberculosis Screening and Treatment Using Cultures and Directly Observed Therapy (CDOT TB TI) identified significantly more tuberculosis cases, including drug-resistant strains, than the previous 1991 guidelines. This improved screening likely reduces TB transmission in both origin and host countries.

More Related Videos

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.8K
A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
10:41

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

15.0K

Related Experiment Videos

Last Updated: Apr 14, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
08:10

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Published on: April 9, 2012

82.3K
The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.8K
A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
10:41

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

15.0K

Area of Science:

  • Public Health
  • Infectious Disease Epidemiology
  • Immigration Health

Background:

  • Rising tuberculosis (TB) incidence in foreign-born populations necessitates effective immigrant screening.
  • Previous TB screening program modifications in the USA have faced effectiveness disputes.
  • This study evaluates the 2009 Technical Instructions for Tuberculosis Screening and Treatment Using Cultures and Directly Observed Therapy (CDOT TB TI) for Chinese permanent resident applicants.

Purpose of the Study:

  • To assess the effectiveness of the 2009 CDOT TB TI compared to the 1991 Technical Instructions (TI).
  • To evaluate the yield of TB cases, including drug-resistant strains, under the new screening protocol.
  • To determine the impact of the CDOT TB TI on TB case detection among immigrants.

Main Methods:

  • Retrospective analysis of demographic, clinical, and laboratory data from Chinese applicants screened between 2009 and 2012.
  • Comparison of TB cases identified by the 1991 TI and the expanded 2009 CDOT TB TI.
  • Evaluation by experienced panel physicians and radiologists using standardized forms.

Main Results:

  • The 2009 CDOT TB TI identified over twice as many TB cases requiring treatment completion (270 vs. 131).
  • The expanded program detected more cases with negative sputum smear but positive culture (181 vs. 44) and more radiographic TB cases.
  • Crucially, the 1991 TI missed 65.79% of drug-resistant isolates, and 81.48% of identified cases were asymptomatic.

Conclusions:

  • The CDOT TB TI, incorporating sputum culture and drug susceptibility testing, significantly increases TB case detection.
  • This enhanced screening likely contributes to reducing TB prevalence in both origin (China) and host (USA) countries.
  • The program effectively identifies asymptomatic and drug-resistant TB cases, improving public health outcomes.