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Updated: Apr 14, 2026

Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
Published on: February 14, 2018
Antifungal therapy for onychomycosis in children
Stephanie Feldstein1, Christine Totri1, Sheila Fallon Friedlander1
1Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital-San Diego and University of California, San Diego School of Medicine, 8010 Frost St. Suite 602, San Diego, CA 92123.
Abstract:
Onychomycosis is a chronic infection of the nail unit, and its prevalence increases with age. Treatment options for children are similar to those for adults and include both oral and topical therapies. Oral agents, such as terbinafine, itraconazole, and fluconazole have been reported to have good efficacy and a low rate of side effects in children. Topical therapies, such as amorolfine and ciclopirox, can also be used as monotherapy or combined with oral agents to treat onychomycosis. Due to their thinner, faster-growing nails, children are more likely to respond to topical monotherapy than adults. There is currently insufficient data comparing emerging medical devices, such as laser therapy, with standard therapeutic options to recommend their use in children.
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