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Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes
Published on: February 19, 2016
Genotoxicity of single-walled carbon nanotubes: in vitro study on human embryonic fibroblast cells
V A Nikitina1, A I Chausheva, I A Suetina
1Medical Genetic Research Center, Russian Academy of Medical Sciences, Moscow, Russia, nikitinava@yandex.ru.
Abstract:
The effects of single-walled carbon nanotubes on the levels of DNA aberrations, chromosome and genome disorders were studied on human embryonic fibroblasts, their karyotype was analyzed by the spectral karyotyping method. The level of DNA aberrations increased after 3-h exposure to the nanotubes. No appreciable increase in the incidence of aberrant metaphases, micronuclei, and chromosome 1, 6, 8, 11, X, and Y aneuploidy after 24- and 48-h incubation with the nanotubes were detected.
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