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Updated: Apr 14, 2026

Preparation of Gynura bicolor DC samples for High-Resolution Tandem Mass Spectrometry
Published on: February 2, 2024
[Chemical constituents of Ligularia songarica]
Objective:
To study the chemical constituents of Ligularia songarica.
Methods:
Isolation and purification were carried out on repeated silica gel column chromatography. The compounds structures were identified by physico-chemical properties and spectral analyses.
Results:
Ten compounds were isolated and identified as benzofuranoeremophil-2-ene (1), 6-angeloyloxy-1,10-epoxy-euryopsin (2), 2-hydroxyplatyphyllide (3), 1β-hydroxy-6,9-dien-8-oxoeremophy-11-nor-11-ketone (4), 2-isopropenyl-6-acetyl-8-methoxy-13-benzodioxin-4-one (5), 1β-hydroxy-6,9-dien-8-oxo-11-nor-11-hydroxyeremophilane (6), isopetasin (7), 6β,10α-dihydroxy-1-oxoeremophila-7 (11), 8(9)-diene-8,12-olide (8), 10α-hydroxy-1-oxo-eremophila-7 (11), 8(9)-diene-8,12-olide (9) and 6β-angeloyloxy-1β,10β-epoxy-9-oxo-furaneremophilane (10).
Conclusion:
Compounds 2-9 are obtained from this plant for the first time.
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