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Updated: Apr 14, 2026

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

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[Inverse psoriasis]

P Weisenseel1, K Reich

  • 1Facharzt für Dermatologie und Venerologie, Allergologie, Dermatologikum Hamburg, Stephansplatz 5, 20354, Hamburg, Deutschland, p.weisenseel@dermatologikum.de.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|April 22, 2015
PubMed

Insights

Inverse psoriasis causes chronic skin inflammation in folds, often with infections. Treatments effective for general psoriasis can be used off-label, improving quality of life.

Area of Science:

  • Dermatology
  • Immunology

Background:

  • Inverse psoriasis presents as chronic inflammatory lesions in skin folds.
  • Secondary infections with Candida or bacteria are common in inverse psoriasis.
  • Reduced quality of life, particularly sexual function, is a significant issue.

Purpose of the Study:

  • To review the clinical presentation and management of inverse psoriasis.
  • To highlight the need for tailored therapy based on clinical outcomes and comorbidities.
  • To discuss treatment options, including off-label use of psoriasis vulgaris therapies.

Main Methods:

  • Literature review of clinical studies and therapeutic guidelines for inverse psoriasis.
  • Analysis of treatment efficacy and safety data.
  • Discussion of differential diagnoses and management strategies.

Main Results:

  • Substances effective for psoriasis vulgaris are generally effective for inverse psoriasis but often require off-label use.
  • Topical ascomycin is one of the few agents with controlled clinical study data for inverse psoriasis.
  • Therapeutic approaches must consider comorbidities and clinical response.

Conclusions:

  • Effective management of inverse psoriasis requires careful diagnosis and individualized treatment plans.
  • Off-label use of established psoriasis treatments is often necessary.
  • Further controlled studies are needed to optimize therapeutic strategies for inverse psoriasis.

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