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Updated: Apr 14, 2026

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
Published on: September 27, 2014
Ebola virus disease: history, epidemiology and outbreaks
Jacqueline Weyer1, Antoinette Grobbelaar, Lucille Blumberg
1Center for Emerging and Zoonotic Diseases, National Institute for Communicable Diseases, 1 Modderfontein Road, Sandringham, Gauteng, 2192, South Africa, jacquelinew@nicd.ac.za.
Abstract:
Over the past 40 years, sporadic Ebola virus disease (EVD) outbreaks have occurred mostly in the central African region. In March 2014, an outbreak of EVD was recognized in Guinea which would become the most significant outbreak of haemorrhagic fever in Africa to date. The outbreak started in Guinea and rapidly spread to Liberia and Sierra Leone, claiming thousands of lives. Many questions still remain regarding the ecology of Ebola viruses, but it is believed that contact with infected bushmeat is an important risk factor for initial spill over of the virus into the human population. At present, there is still no registered prophylaxis or curative biologicals against EVD.
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