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Related Experiment Video

Updated: Apr 14, 2026

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
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Postmortem stability of Ebola virus.

Joseph Prescott, Trenton Bushmaker, Robert Fischer

    Emerging Infectious Diseases
    |April 22, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Viable Ebola virus can be isolated from corpses for up to 7 days after death. Viral RNA remains detectable for 10 weeks, impacting public health and forensic investigations during outbreaks.

    Keywords:
    Ebola hemorrhagic feverEbola virusEbola virus diseaseWest Africacynomolgus macaquesoutbreakpostmortem stabilitytransmissionviruses

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    Area of Science:

    • Virology
    • Infectious Diseases
    • Public Health

    Background:

    • The West Africa Ebola virus outbreak raised concerns about virus stability in corpses.
    • Accurate detection of viral RNA in deceased individuals is crucial for disease surveillance and control.

    Purpose of the Study:

    • To determine the duration of viable Ebola virus and detectable viral RNA in deceased individuals.
    • To model post-mortem stability of Ebola virus using a non-human primate model.

    Main Methods:

    • Ebola virus-infected macaques were used as a model for human Ebola virus disease deaths.
    • Samples were collected post-euthanasia to assess viable virus isolation and RNA detection.

    Main Results:

    • Viable Ebola virus was successfully isolated for less than 7 days post-euthanasia.
    • Ebola virus RNA was detectable in samples for up to 10 weeks after euthanasia.

    Conclusions:

    • Ebola virus can remain viable in corpses for a limited period, posing potential risks.
    • Viral RNA detection persists significantly longer than viable virus, with implications for post-mortem diagnostics.