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Rapid Detection of Acquired and Inducible Clarithromycin Resistance in Mycobacterium abscessus Group by a Simple
Robert F Luo1, Cheyenne Curry2, Nathan Taylor2
1Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.
Journal of Clinical Microbiology
|April 24, 2015
Abstract:
By targeting the erm(41) and rrl genes in the Mycobacterium abscessus group, a multiplex real-time PCR assay for clarithromycin resistance showed 95% (38/40) concordance with nucleic acid testing and 95% (37/39) concordance with phenotypic testing. This assay provides a simple and rapid alternative to extended incubation or erm(41) sequencing.

