Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Immunogenicity signals 1,2,3 ... and 0.

Immunology Today

|September 1, 1989

Summary

The immune system distinguishes self from non-self to prevent infection and autoimmunity. This summary explores lymphocyte activation signals and proposes a new hypothesis for immune system function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The immune destruction of pancreatic β cells.

Immunology today·2014

Same author

Fly immunity: great expectations.

Genome biology·2000

Same author

The Toll receptor family and microbial recognition.

Trends in microbiology·2000

Same author

Viral interference with IL-1 and toll signaling.

Proceedings of the National Academy of Sciences of the United States of America·2000

Same author

Innate immunity.

The New England journal of medicine·2000

Same author

Innate immune recognition: mechanisms and pathways.

Immunological reviews·2000

Area of Science:

Immunology
Cellular Biology
Autoimmunity

Background:

The immune system's ability to differentiate self from non-self is crucial for health.
Failure in self-tolerance can result in autoimmune diseases.
Failure to respond to non-self pathogens can lead to severe infections.

Discussion:

This summary focuses on signals that induce lymphocyte activation, a key topic from the 'Immunogenicity' conference.
The discussion centers on the mechanisms governing the initiation of adaptive immune responses.
Understanding these signals is vital for comprehending immune system regulation.

Key Insights:

Key signals involved in lymphocyte activation were a central theme.
An emerging hypothesis regarding immune system function is presented.
The findings offer insights into maintaining immune homeostasis.

Outlook:

Further research into lymphocyte activation signals could reveal new therapeutic targets for autoimmune diseases.
The proposed hypothesis requires experimental validation.
Continued investigation into immunogenicity is essential for advancing immunology.

Related Experiment Videos