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Intravenous Anesthesia With Bispectral Index Monitoring vs Inhalational Anesthesia for Rhytidoplasty: A Randomized
Kristin A Jones1, Keith A LaFerriere2
1Lexington Facial Plastic Surgery, Lexington, Kentucky.
The propofol and ketamine hydrochloride anesthesia with bispectral index monitoring (PKA-BIS) protocol offers a comparable alternative to inhalational anesthesia (IA) for rhytidoplasty patients. This study found reduced emergence and discharge times with PKA-BIS, though other outcomes require further investigation.
Area of Science:
- Anesthesiology
- Surgical Outcomes
- Patient Recovery
Background:
- Minor anesthesia-related adverse effects are common and concerning for patients.
- Intravenous anesthesia protocols have shown promise in reducing postoperative nausea, vomiting, and pain.
Purpose of the Study:
- To compare postoperative outcomes between a combined propofol and ketamine hydrochloride anesthesia with bispectral index monitoring (PKA-BIS) protocol and inhalational anesthesia (IA).
- The study focused on patients undergoing lower rhytidoplasty.
Main Methods:
- A prospective, double-blind, randomized trial involving 30 female patients undergoing rhytidoplasty.
- Outcomes measured included nausea, vomiting, pain, well-being, emergence time, discharge time, and cost, assessed via QOR-40 and VAS questionnaires.
Main Results:
- The PKA-BIS group showed statistically significant reductions in emergence time (29.8 vs 46.0 min) and time to discharge criteria (51.4 vs 66.1 min).
- Trends towards decreased nausea, vomiting, and confusion were observed in the PKA-BIS group, but did not reach statistical significance.
- No significant differences were found in global recovery scores, overall well-being, or pain perception between the groups. Anesthesia costs were similar.
Conclusions:
- The PKA-BIS protocol is a viable alternative to IA for rhytidoplasty.
- Larger studies are needed to confirm the significance of observed trends in reducing postoperative adverse events and pain.
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