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Author Spotlight: Innovative Use of nsPEF to Boost Peripheral Nerve Regeneration
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Pathways Mediating Activity-Induced Enhancement of Recovery From Peripheral Nerve Injury
Manning J Sabatier1, Arthur W English
11Departments of Rehabilitation Medicine and 2Cell Biology, Emory University School of Medicine, Atlanta, GA.
Exercise and Sport Sciences Reviews
|April 24, 2015
Abstract:
This article outlines the novel hypothesis that exercise promotes axon regeneration after peripheral nerve injury through neuronal brain-derived neurotrophic factor (BDNF), and there are three required means of promoting BDNF expression: 1) increased signaling through androgen receptors, 2) increased cAMP-responsive element-binding protein expression, and 3) increased expression of the transcription factor SRY-box containing gene 11.

