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Antiplatelet and anticoagulant therapy after intracerebral hemorrhage

Allyson Zazulia1

  • 1Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8111, St Louis, MO 63110, USA.

Neurologic Clinics
|April 25, 2015
PubMed

Management of patients with an indication for long-term oral antithrombotic therapy who have an intracerebral hemorrhage (ICH) presents a therapeutic dilemma. Should antithrombotic therapy be resumed, and if so, when, using what agent, and for whom? There is no consensus for answers to these questions. In the absence of randomized trials, management of antithrombotic therapy after ICH is based on a combination of observational data, pathophysiologic concepts, and decision analysis. At the heart of the decision is an assessment of the individual patient's risk of thromboembolism off antithrombotic therapy versus risk of ICH recurrence on antithrombotic therapy.

Keywords:
AnticoagulationAntiplatelet therapyAtrial fibrillationIntracerebral hemorrhageProsthetic heart valveVenous thromboembolism

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