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Related Concept Videos

Exercise and Cardiac Output01:17

Exercise and Cardiac Output

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Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
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Related Experiment Video

Updated: Apr 14, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
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Vigorous Exercise Can Cause Abnormal Pulmonary Function in Healthy Adolescents.

Alladdin Abosaida1,2, Jen Jen Chen1,2, Eliezer Nussbaum1,2

  • 11 Department of Pediatrics, School of Medicine, University of California, Irvine (UC Irvine), Irvine, California.

Annals of the American Thoracic Society
|April 25, 2015
PubMed
Summary

Healthy adolescents can experience exercise-induced bronchoconstriction. More rigorous exercise tests, like the ramp protocol, may better detect this condition in individuals with normal responses to standard exercise challenges.

Keywords:
exercise physiologyexercise testingexercise-induced bronchoconstriction

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Area of Science:

  • Pediatric Pulmonology
  • Exercise Physiology

Background:

  • Exercise-induced bronchoconstriction (EIB) occurs in healthy adolescents, not just those with asthma.
  • The American Thoracic Society (ATS) recommends steady-state exercise tests for diagnosing EIB.
  • Vigorous exercise may reveal EIB missed by standard tests, possibly due to airway dehydration from hyperventilation.

Purpose of the Study:

  • To compare the effects of constant work rate and progressive ramp exercise protocols on pulmonary function in healthy adolescents.
  • To test the hypothesis that vigorous exercise protocols reduce lung function in healthy adolescents.

Main Methods:

  • 56 healthy adolescents (mean age 15.2 years) underwent two protocols: ATS-recommended constant work rate and a standardized progressive ramp test.
  • Pulmonary function abnormalities were defined as a >10% decline in FEV1 from baseline.
  • Bronchoconstriction was assessed using ATS criteria.

Main Results:

  • 17.8% of participants (10/56) showed a significant FEV1 drop post-exercise.
  • Abnormal lung function was detected after the ramp test in 50% of these cases, after the ATS test only in 30%, and after both in 20%.

Conclusions:

  • Healthy adolescents can exhibit subtle, exercise-induced bronchoconstriction.
  • Both constant work rate and progressive ramp protocols can detect EIB in this population.
  • Ramp testing is a valuable consideration for adolescents with suspected EIB who have normal results on steady-state tests.