Tissue difference in cellular localization of thiamine phosphate esters
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Updated: Oct 20, 2026

Brain Slice Biotinylation: An Ex Vivo Approach to Measure Region-specific Plasma Membrane Protein Trafficking in Adult Neurons
Published on: April 3, 2014
T Matsuda1, H Tonomura, A Baba
1Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University, Japan.
Abstract:
1. Thiamine phosphate levels were determined in the soluble and particulate fractions of various rat tissues. 2. There was marked tissue difference in the cellular localization of thiamine phosphates. 3. Brain thiamine triphosphate was localized only in the particulate fraction, whereas skeletal muscle thiamine triphosphate was in the soluble fraction as a protein-unbound form.
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