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Updated: Apr 14, 2026

Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection
Published on: October 25, 2013
[Physiological properties of the vancomycin-resistant strain Staphylococcus epidermidis 33 GISK VAN(R)]
Abstract:
Physiological properties of a selected Staphylococcus epidermidis strain 33 GISK VAN(R) with high resistance to vancomycin, multiple resistance to various antibiotics, as well as decreased sensitivity to lysozyme, lysostaphin, and the low-molecular mass peptide warnerin were studied. The strain was characterized by a thicker cell wall, resulting in considerably decreased rates of vancomycin penetration into the cells and in limited access of the antibiotic to its targets on the bacterial membrane.
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