Related Experiment Video
Updated: Apr 14, 2026
07:27
Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
Published on: December 18, 2012
12.5K
Dyshidrosis is a risk factor for herpes zoster
Summary
Individuals with dyshidrosis have a significantly increased risk of developing herpes zoster (HZ). Early awareness and monitoring for HZ are crucial for patients diagnosed with dyshidrosis.
Area of Science:
- Dermatology
- Epidemiology
- Immunology
Background:
- Dyshidrosis is linked to immune system reactivity.
- Herpes zoster (HZ) incidence rises with immune deficiencies, suggesting a potential connection to dyshidrosis.
Purpose of the Study:
- To investigate the association between dyshidrosis and the incidence of herpes zoster (HZ).
Main Methods:
- Population-based cohort study utilizing Taiwan's Longitudinal Health Insurance Database (LHID2000) from 1996-2011.
- 8,488 patients with newly diagnosed dyshidrosis (no prior HZ) were compared to matched controls without dyshidrosis.
Main Results:
- Patients with dyshidrosis showed a 1.31 hazard ratio for HZ after adjusting for risk factors.
- Dyshidrosis patients exhibited a higher HZ risk, irrespective of comorbidities.
- Increased hospital visits for dyshidrosis correlated with a greater risk of HZ.
Conclusions:
- A strong association exists between dyshidrosis and herpes zoster (HZ).
- Healthcare providers should inform dyshidrosis patients about their elevated HZ risk.
Related Concept Videos
01:26Factors Affecting the Risk of Infection
14.7K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.7K
01:23Skin Diseases and Disorders
6.3K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.3K
01:01Hypersensitivity Reactions: Cytolytic Reactions
150
Type II hypersensitivity involves IgG and IgM antibodies targeting cell surface antigens, leading to cell destruction. This can occur through complement activation, antibody-dependent cell-mediated cytotoxicity (ADCC), or acting as opsonins for phagocytosis. When excessive, these reactions cause significant tissue damage.Drug-induced hemolytic anemia is a common example, where drugs like penicillin or cephalosporins bind to red blood cells, forming drug-protein complexes. These complexes...
150
01:28Diphtheria
124
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
124
01:29Hypersensitivity Reactions: Delayed Hypersensitivity Reactions
248
Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...
248
01:19Hypersensitivity Reactions: Immune-Complex Reactions
207
Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum...
207