Related Experiment Video
Updated: Apr 14, 2026

A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
Published on: August 11, 2018
Prospective adherence to specific immunotherapy in Europe (PASTE) survey protocol
Melina Makatsori1, Gianenrico Senna2, Constantinos Pitsios3
1Royal Brompton and Harefield NHS Trust, London, UK ; Imperial College London, National Heart and Lung Institute, London, UK.
This study surveyed over 1,350 adults across Europe to understand adherence to allergen immunotherapy (subcutaneous and sublingual). The goal is to identify factors affecting treatment adherence in real-world clinical practice.
Area of Science:
- Allergy and Immunology
- Clinical Research Methodology
Background:
- Allergen immunotherapy adherence is crucial for treatment efficacy.
- Real-world data on allergen immunotherapy adherence is limited.
- A European initiative aimed to prospectively evaluate adherence.
Purpose of the Study:
- To evaluate adherence to subcutaneous and sublingual immunotherapy in a real-life clinical setting.
- To identify factors influencing adherence across diverse European countries.
- To inform strategies for improving patient adherence to immunotherapy.
Main Methods:
- A prospective, multi-country online survey was conducted.
- Adults with respiratory allergies or Hymenoptera venom allergy were enrolled.
- Participants were followed for three years, with 4-monthly adherence assessments.
Main Results:
- Over 1,350 participants were enrolled across 45 centers in eight European countries.
- The study utilized online survey software for data collection.
- Data collection focused on adherence and reasons for missed doses or treatment discontinuation.
Conclusions:
- Online survey tools facilitated a large-scale, multi-country study.
- The findings are expected to enhance understanding of immunotherapy adherence.
- This research aims to guide improvements in patient adherence strategies.
More Related Videos
06:28E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
09:03Rapid In Vivo Assessment of Adjuvant's Cytotoxic T Lymphocytes Generation Capabilities for Vaccine Development
Published on: June 19, 2018
Related Concept Videos
Bioavailability Study Design: Healthy Subjects Versus Patients
Clinical Trials: Overview
Clinical Trials
There are four phases in a clinical trial. A phase one...
Bioequivalence studies: Biowaivers