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Desmoplastic infantile ganglioglioma with associated giant aneurysm—case report
Chiu Yuen To1, Gary Rajah, Elizabeth Klein
1Department of Neurosurgery, Detroit Medical Center, Wayne State University, Detroit, MI, USA, tochiuyuen@gmail.com.
Insights
This report details an extremely rare case of an infant diagnosed with both desmoplastic infantile ganglioglioma (DIG) and a giant cerebral aneurysm. This co-occurrence has not been previously documented in medical literature.
Area of Science:
- Pediatric neurosurgery
- Neuroradiology
- Neuropathology
Background:
- Desmoplastic infantile ganglioglioma (DIG) is a rare, aggressive embryonal tumor typically occurring in infants.
- Supratentorial giant cerebral aneurysms are exceptionally uncommon vascular malformations in the pediatric population.
Observation:
- A case presentation of an 8-day-old male infant with concurrent diagnoses of DIG and a supratentorial giant cerebral aneurysm.
- Detailed clinical, radiological, and pathological findings of both conditions in the infant.
Findings:
- The simultaneous presence of DIG and a giant cerebral aneurysm in an infant is unprecedented.
- Discussion of the diagnostic challenges and potential pathophysiological links between these rare entities.
Implications:
- Highlights the importance of comprehensive evaluation in infants presenting with rare neurological conditions.
- Suggests potential, yet unexplored, associations between brain tumors and vascular malformations in early life.
- Contributes to the limited literature on coexisting pediatric brain tumors and aneurysms.
Abstract:
Desmoplastic infantile ganglioglioma (DIG) and supratentorial giant cerebral aneurysm are each extremely rare entities in infants. Here, we present the case of an 8-day old boy who had both of these conditions concurrently. To our knowledge, there is no previous case reported of a patient with coexisting DIG and giant aneurysm.
