Related Experiment Video
Updated: Aug 17, 2026

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
Improved counting efficiencies for measuring 239Pu in the lung in the sitting position
H E Palmer1, G A Rieksts, S J Jefferies
1Pacific Northwest Laboratory, Richland, WA 99352.
Measuring lung deposition with Ge and Phoswich detectors showed significant efficiency increases when subjects sat up compared to lying down. This improved lung counting efficiency is linked to reduced tissue absorption and closer detector proximity.
Area of Science:
- Nuclear physics
- Radiological protection
- Medical imaging
Background:
- Accurate lung deposition measurements are crucial for assessing internal radiation exposure.
- Previous lung counting techniques faced challenges with variable body positions affecting detector efficiency.
Purpose of the Study:
- To quantify the impact of body positioning on lung counting efficiency for inhaled radionuclides.
- To compare the effectiveness of Ge planar and Phoswich detector systems in different positions.
Main Methods:
- Lung deposition measurements of 92mNb were performed on 10 women in supine and sitting positions.
- Two detector systems, Ge planar and Phoswich, were utilized for counting.
- Chest wall thickness was measured to correlate with counting efficiency changes.
Main Results:
- Sitting position increased counting efficiency by an average of 108% (Ge) and 310% (Phoswich) compared to supine.
- Individual efficiency gains ranged from 15-260% (Ge) and 40-480% (Phoswich).
- Efficiency increase correlated with chest wall thickness, suggesting reduced tissue absorption and improved geometry.
Conclusions:
- The sitting position significantly enhances lung counting efficiency for inhaled radionuclides.
- Phoswich detectors showed a more substantial improvement in efficiency than Ge detectors with positional changes.
- Chest wall thickness and source-to-detector geometry are key factors influencing lung counting accuracy.
Related Concept Videos
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET

