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Updated: Apr 13, 2026

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Rash with DERMABOND PRINEO Skin Closure System Use in Bilateral Reduction Mammoplasty: A Case Series.

R W Knackstedt1, J A Dixon1, P J O'Neill1

  • 1MUSC Division of Plastic Surgery, 96 Jonathan Lucas Street, CSB 404, MSC 613, Charleston, SC 29425, USA.

Case Reports in Medicine
|April 30, 2015
PubMed
Summary
This summary is machine-generated.

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Allergic reactions to DERMABOND PRINEO Skin Closure System can occur after bilateral reduction mammoplasty. Caution is advised for patients with prior adhesive allergies or in moist areas.

Area of Science:

  • Plastic Surgery
  • Dermatology
  • Wound Healing

Background:

  • Bilateral reduction mammoplasty is prone to scar formation.
  • Surgical adhesives offer an alternative to sutures for wound closure.
  • DERMABOND PRINEO Skin Closure System combines adhesive with a mesh for wound closure.

Purpose of the Study:

  • To describe three cases of allergic reactions to DERMABOND PRINEO Skin Closure System.
  • To explore the safety profile of DERMABOND PRINEO Skin Closure System in plastic surgery.

Main Methods:

  • Retrospective chart review of bilateral reduction mammoplasty patients.
  • Identification of patients who developed a rash after using DERMABOND PRINEO Skin Closure System.

Main Results:

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  • Three patients experienced allergic reactions (rash) to DERMABOND PRINEO Skin Closure System post-mammoplasty.
  • Allergic reactions required systemic steroid treatment.
  • One patient had a history of prior adhesive allergy.

Conclusions:

  • DERMABOND PRINEO Skin Closure System is effective for scar healing but carries a risk of allergic reactions.
  • Caution is recommended for patients with a history of adhesive allergy.
  • Avoid use in areas prone to moisture or friction to minimize reaction risk.