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Travellers' diarrhoea.

Christopher Stewart Heather¹

¹Department of Microbiology and Infectious Diseases, Liverpool Hospital, Sydney, Australia.

BMJ Clinical Evidence

|May 1, 2015

Summary

This summary is machine-generated.

Travelers' diarrhea affects many international travelers. This review evaluates treatments like antibiotics and oral rehydration solutions for acute mild-to-moderate cases.

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Area of Science:

Travel Medicine
Infectious Diseases
Gastroenterology

Background:

An estimated 30% to 70% of international travelers experience diarrhea.
This condition can occur during travel or upon returning home.
Diarrhea poses a significant health concern for global travelers.

Purpose of the Study:

To systematically review treatments for acute mild-to-moderate travelers' diarrhea.
To assess the effectiveness and safety of various interventions.
Focus on adults traveling from resource-rich to resource-poor countries.

Main Methods:

Systematic review of multiple databases (Medline, Embase, Cochrane Library).
Inclusion of 24 studies meeting predefined criteria.
GRADE evaluation of evidence quality for interventions.

Main Results:

Evaluated interventions include antibiotics, antimotility agents, bismuth subsalicylate, diet, oral rehydration solutions, and racecadotril.
Data synthesized to assess treatment efficacy and safety.
Consideration of harms alerts from regulatory agencies.

Conclusions:

The review provides comprehensive information on interventions for travelers' diarrhea.
Effectiveness and safety profiles of different treatments are presented.
Guidance for managing travelers' diarrhea in specific populations is offered.