Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visuospatial working memory in Parkinson's disease.

V A Bradley1, J L Welch, D J Dick

  • 1Regional Neurological Centre, General Hospital, Newcastle upon Tyne.

Journal of Neurology, Neurosurgery, and Psychiatry
|November 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of "Off-Target" Immune Modulation Induced by Live Attenuated Yellow Fever Vaccine.

The Journal of infectious diseases·2023
Same author

Measuring coping in people with amyotrophic lateral sclerosis using the Coping Index-ALS: A patient derived, Rasch compliant scale.

Journal of the neurological sciences·2021
Same author

Development and validation of Spasticity Index-Amyotrophic Lateral Sclerosis.

Acta neurologica Scandinavica·2018
Same author

Zebra body myopathy is caused by a mutation in the skeletal muscle actin gene (ACTA1).

Neuromuscular disorders : NMD·2015
Same author

Ultrahigh-noise rejection optical filter.

Optics letters·2009
Same author

Course and outcome of acute limbic encephalitis with negative voltage-gated potassium channel antibodies.

Journal of neurology, neurosurgery, and psychiatry·2006
Same journal

Cancer risk and mortality in patients with multiple sclerosis in Finland: a retrospective population-based cohort study.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Visuospatial working memory in Huntington's disease: behavioural and structural brain correlates.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Characteristics and outcomes in electric scooter-related traumatic brain injuries in Helsinki.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Chronological ageing and ovarian reserve in MS: insights from anti-Müllerian hormone and disability progression.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Durable fluoropolymer drug-eluting stent versus bare-metal stent for the prevention of intracranial in-stent restenosis.

Journal of neurology, neurosurgery, and psychiatry·2026
Same journal

Correction: <i>How well do plasma Alzheimer's disease biomarkers reflect the CSF amyloid status?</i>

Journal of neurology, neurosurgery, and psychiatry·2026
See all related articles

Parkinson's disease patients show significant visuospatial working memory deficits. This impairment stems from difficulty utilizing stored information, not reduced capacity, impacting complex task performance.

Area of Science:

  • Neuroscience
  • Cognitive Psychology

Background:

  • Visuospatial impairment is common in Parkinson's disease (PD).
  • The underlying psychological mechanisms and breakdown pathways remain unclear.

Purpose of the Study:

  • To investigate if the visuospatial subsystem of working memory is impaired in Parkinson's disease.
  • To determine if performance deficits result from capacity reduction or information utilization difficulties.

Main Methods:

  • Compared 16 mild-to-moderate Parkinson's disease patients with a matched control group.
  • Administered complex visuospatial and verbal working memory tasks.

Main Results:

  • Parkinson's disease group was significantly slower on visuospatial tasks.

Related Experiment Videos

  • No significant difference in speed or errors on verbal tasks compared to controls.
  • Findings support impairment in the visuospatial working memory subsystem.
  • Conclusions:

    • The visuospatial working memory subsystem is impaired in Parkinson's disease.
    • The deficit is characterized by difficulties in information utilization, not capacity reduction.