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B-cell acquisition of antigen: Sensing the surface

Andrew M Knight1

  • 1The Institute of Cellular Medicine, The Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, UK.

European Journal of Immunology
|May 2, 2015
PubMed
Summary

B cells recognize antigens differently based on surface stiffness. Less stiff surfaces enhance B-cell activation and antibody production, potentially revealing new immune sensing mechanisms.

Keywords:
APCAnergyAntigen processing and presentationAutoimmunityB cellDamageMHCStiffnessTumor immunity

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