Related Experiment Video
Updated: Apr 13, 2026

07:52
In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
Published on: November 22, 2021
4.0K
Neural control of hand movements
1Dept. of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA.
Motor Control
|May 2, 2015
Summary
Understanding hand movement control is crucial. This study explores complex neuronal pathways using brain stimulation in healthy individuals and those with spinal cord injuries to map voluntary muscle activity.
Area of Science:
- Neuroscience
- Motor Control
- Neurophysiology
Background:
- Hand movements are fundamental to daily activities.
- The neural control of hand actions involves intricate cortical and subcortical pathways.
- Understanding these pathways is essential for addressing neurological disorders affecting hand function.
Purpose of the Study:
- To elucidate the complex neuronal pathways governing voluntary hand movements.
- To investigate the roles of contralateral and ipsilateral influences on hand motor control.
- To explore potential therapeutic targets for improving hand function in health and disease.
Main Methods:
- Utilizing transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (TES).
- Employing these neurostimulation techniques in healthy human subjects.
- Conducting studies on individuals with chronic incomplete spinal cord injury.
Main Results:
- Task-dependent modulations in cortical and subcortical pathways were observed.
- Evidence suggests significant contralateral and ipsilateral influences on hand muscle activity.
- Neurostimulation revealed insights into the neural control mechanisms in both healthy and injured states.
Conclusions:
- The study enhances our understanding of the neural basis of hand movement control.
- Findings provide a foundation for developing interventions for conditions impacting hand function.
- Further research into these pathways can inform rehabilitation strategies for spinal cord injury.
Related Concept Videos
Hierarchy of Motor Control
6.9K
The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.
6.9K
Direct Motor Pathways
5.3K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
5.3K
Spinal Nerves: Plexus I
3.6K
Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
3.6K
Brainstem
8.4K
The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
8.4K
Muscles of the Forearm that Move the Hand and Fingers
3.3K
The muscles of the forearm that move the wrist, hand, and digits are numerous and diverse. They can be classified into two groups based on their location and function — the anterior and posterior compartment muscles.
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi...
Anterior Compartment
The anterior compartment muscles originate from the humerus. They primarily function as flexors and are also known as flexor muscles. They typically insert on the carpals, metacarpals, and phalanges. The superficial layer includes the flexor carpi...
3.3K
Indirect Motor Pathways
3.9K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
3.9K

