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Updated: Apr 13, 2026
Expansion of Human Peripheral Blood γδ T Cells using Zoledronate
Published on: September 9, 2011
Primary cutaneous γ/δ T-cell lymphoma. An atypical case with bone marrow granulomas
Guy Shalom1, Ronit Gurion2, Daniel Benharroch3
1Department of Dermatology and Venereology, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;
Background:
Primary cutaneous γ/δ T-cell lymphoma is a rare variant of peripheral T-cell lymphoma which has been only recently set apart from subcutaneous panniculitis-like T-cell lymphoma and is known for its aggressive nature.
Main Observation:
We hereby report a case of primary cutaneous γ/δ T-cell lymphoma in a 35-year-old man with bone marrow granulomas, an unexpected feature in this lymphoma. The patient was treated with combination chemotherapy. Partial response was obtained, followed by relapse. Allogeneic stem cell transplantation was then carried out, and full remission was achieved.
Conclusion:
Bone marrow granulomas can be an accompanying feature in primary cutaneous γ/δ T-cell lymphoma.
