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Blood parameters as indicators of upper airway obstruction in children with adenoid or adenotonsillar hypertrophy

Gokce Simsek1, Ceren Karacayli, Aysenur Ozel

  • 1*ENT Department, Faculty of Medicine, Kirikkale University, Kirikkale †Clinic of Social Pediatrics, Dr. Sami Ulus Maternity and Children's Training and Research Hospital, Ministry of Health, Ankara ‡Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.

The Journal of Craniofacial Surgery
|May 2, 2015
PubMed

Insights

Adenotonsillar hypertrophy (ATH) surgery significantly alters blood parameters in children. Adenotonsillectomy shows more substantial improvements in blood markers compared to adenoidectomy alone, addressing chronic hypoxia.

Area of Science:

  • Pediatric Otolaryngology
  • Sleep Medicine
  • Hematology

Background:

  • Adenotonsillar hypertrophy (ATH) is the primary cause of pediatric obstructive sleep apnea.
  • Chronic hypoxia associated with ATH can impact systemic health and blood parameters.

Purpose of the Study:

  • To evaluate changes in blood parameters in children with ATH following surgical intervention.
  • To compare the effects of adenoidectomy versus adenotonsillectomy on these blood markers.

Main Methods:

  • Retrospective review of 130 children undergoing adenoidectomy or adenotonsillectomy for ATH.
  • Comparison of pre- and post-operative blood parameters including white blood cell count, platelet count, hemoglobin, mean platelet volume, and platelet distribution width.
  • Inclusion of a healthy control group (n=82) for baseline comparison.

Main Results:

  • Surgery led to decreased mean platelet volume, platelet distribution width, and hemoglobin levels.
  • Significant decreases were observed in the adenotonsillectomy group (Group 2) compared to the adenoidectomy group (Group 1).
  • White blood cell count increased significantly in the adenotonsillectomy group, while platelet counts showed no significant change.

Conclusions:

  • Upper airway obstruction from ATH significantly alters blood parameters linked to chronic hypoxia.
  • Adenotonsillectomy demonstrates more significant improvements in blood parameters than adenoidectomy alone.
  • Surgical intervention, particularly adenotonsillectomy, can ameliorate blood parameter changes associated with chronic hypoxia in children with ATH.
Abstract

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