[Atypical presentation in Kimura's disease].

Area of Science:

• Pathology
• Immunology
• Dermatology

Background:

• Kimura's disease is a rare chronic inflammatory disorder of unknown etiology.
• It commonly affects salivary glands and subdermal tissues in the head and neck.
• Systemic involvement, such as nephrotic syndrome secondary to glomerulonephritis, can also occur.

Observation:

• A 57-year-old male presented with a slowly progressing 3x3 cm mass in his right buccal region over two years.
• The mass was soft to palpation and excised via an intraoral approach.
• Histopathological examination confirmed Kimura's disease.

Findings:

• Characteristic histological features include follicular hyperplasia, eosinophil infiltration, and postcapillary venule proliferation.
• Differential diagnosis is crucial, as Kimura's disease can mimic angiolymphoid hyperplasia with eosinophilia.
• Complete surgical excision was the chosen treatment modality for this patient.

Implications:

• This case highlights the importance of considering Kimura's disease in the differential diagnosis of head and neck masses.
• Accurate histopathological identification is key for appropriate management.
• Further research into the etiology of Kimura's disease is warranted.