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Published on: August 1, 2025
Vγ9Vδ2-T cells as antigen presenting cells for iNKT cell based cancer immunotherapy
Inge M Werter1, Famke L Schneiders1, Emmanuel Scotet2
1Department of Medical Oncology; VU University Medical Center ; Amsterdam, The Netherlands.
Abstract:
CD1d-restricted invariant natural killer T cells (iNKT) constitute an important immunoregulatory T-cell subset involved in the induction of antitumor immune responses. Here, we provide a view on the recent observation that Vγ9Vδ2-T cells, through trogocytosis of CD1d-containing membrane fragments, have the capacity to act as antigen presenting cells for iNKT.
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