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Incidence trends for childhood type 1 diabetes in India
Kanakatte Mylariah Prasanna Kumar1
1Consultant Endocrinologist, Centre for Diabetes and Endocrine Care, Bangalore Diabetes hospital, Bengaluru, Karnataka, India.
Insights
Type 1 diabetes mellitus (T1DM) affects an estimated 97,700 children in India. Studies reveal T1DM is more prevalent in India than in many Asian countries, with varying rates across regions.
Area of Science:
- Pediatrics
- Endocrinology
- Public Health
Background:
- Type 1 diabetes mellitus (T1DM) is a significant health concern in children.
- Estimates suggest a substantial number of children in India live with T1DM.
- Previous studies indicated T1DM prevalence in specific Indian regions.
Purpose of the Study:
- To estimate the prevalence and incidence of T1DM in children across various regions of India.
- To compare T1DM rates in India with other Asian countries.
- To identify regional variations in T1DM diagnosis and prevalence.
Main Methods:
- Analysis of data from a 1992 population-based study in South India.
- Review of the Karnataka state T1DM registry data over 13 years.
- Examination of prevalence data from Karnal, Haryana, distinguishing urban and rural areas.
Main Results:
- The first South India study reported a prevalence of 0.26/1000 children, with a peak diagnosis age of 12 years.
- Karnataka's T1DM registry showed incidence rates of 3.7-4.0/100,000 children.
- Karnal district reported an average T1DM prevalence of 10.20/100,000, with urban areas at 26.6/100,000.
Conclusions:
- Insulin-dependent diabetes (T1DM) is not rare in Indian children and its prevalence is higher than in many Asian nations.
- Significant regional variations in T1DM prevalence exist within India.
- An estimated 18,000 new cases of T1DM in children under 15 were diagnosed in 2011 in the studied regions.
Abstract:
It is estimated that India is housing about 97,700 children with type 1 diabetes mellitus (T1DM). A study of 30 children with insulin-dependent diabetes with age at diagnosis ≤15 years, conducted in 1992, reported a prevalence of 0.26/1000 children. The peak age at diagnosis was 12 years. This was the first population-based study of prevalence of insulin-dependent diabetes in South India and shows that insulin-dependent diabetes is not rare and is higher than that reported from many other Asian countries. The Karnataka state T1DM registry listed an incidence of 3.7/100,000 in boys and 4.0/100,000 in girls over 13 years of data collection. At Karnal, in Haryana, the prevalence of T1DM is 26.6/100,000 in urban and 4.27/100,000 in rural areas of the district, leading to an average prevalence of 10.20/100,000 population. Karnal city has a relatively high prevalence of T1DM (31.9/100,000). An estimated 18,000 children under the age of 15 were newly diagnosed for T1DM in the year 2011 in the above-mentioned regions. The prevalence of T1DM in children is 111,500 according to a World Health Organization report of the International Diabetes Federation for the South-East Asian Region.
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