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Related Concept Videos

Burn Injuries01:22

Burn Injuries

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Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
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Clinical Applications of Epidermal Stem Cells01:19

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Skin substitutes in burn care.

Wounds : a compendium of clinical research and practice·2015
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Skin grafting in burns.

Chester N Paul1

  • 1Saint Elizabeth's Regional Burn and Wound Care Center, Lincoln, NE;

Wounds : a Compendium of Clinical Research and Practice
|May 6, 2015
PubMed
Summary

This review traces the history of skin grafting for burn injuries from ancient times to modern techniques. Key advancements include the development of mechanical dermatomes and meshers, leading to current early excision and grafting practices.

Area of Science:

  • Plastic Surgery
  • Burn Care
  • Dermatology

Background:

  • Skin grafting has been utilized for wound treatment for centuries.
  • Early methods were rudimentary, with limited success.
  • Burn injuries present unique challenges for wound healing and reconstruction.

Purpose of the Study:

  • To provide a comprehensive historical review of skin grafting techniques in burn injury management.
  • To identify key milestones and innovations in the evolution of burn care surgery.
  • To contextualize current best practices in the historical development of skin grafting.

Main Methods:

  • A systematic literature search was conducted using Medline and Google Scholar.
  • Keywords included 'skin graft,' 'autograft,' 'allograft,' 'xenograft,' 'burn surgery,' 'burn excision,' and 'burn grafting.'

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  • Relevant articles and their bibliographies were reviewed to trace the historical progression.

    • Main Results:

    • The earliest documented successful skin graft publication dates to 1869 by J.L. Reverdin.
    • Significant technological advancements include the introduction of mechanical dermatomes in the 1930s and mechanical meshers in the 1960s.
    • The practice of early excision and grafting has become a standard in contemporary burn care.

    Conclusions:

    • The history of skin grafting in burn injuries demonstrates a gradual but impactful evolution of surgical techniques.
    • Technological innovations have been crucial in improving the efficacy and application of skin grafts.
    • Early excision and grafting represent a culmination of historical advancements, forming the foundation of modern burn treatment.